EUR
en
Product Name L-Nicotine
Synonyms B-Pyridyl-a-N-Methylpyrrolidine.; S-(-)-Nicotine
Recommended Use Laboratory chemicals.
Uses advised against Food, drug, pesticide or biocidal product use.
This chemical is considered hazardous according to [US] OSHA (29 CFR 1910.1200, 2024)
Signal Word Danger
Hazard Statements Fatal if swallowed, in contact with skin or if inhaled
Wash face, hands and any exposed skin thoroughly after handling
Do not eat, drink or smoke when using this product
Do not get in eyes, on skin, or on clothing
Wear protective gloves/protective clothing/eye protection/face protection
Do not breathe dust/fume/gas/mist/vapors/spray
Use only outdoors or in a well-ventilated area
Wear respiratory protection
Get medical attention/advice if you feel unwell
IF INHALED: Remove person to fresh air and keep comfortable for breathing
Immediately call a POISON CENTER or doctor
Call a POISON CENTER or doctor if you feel unwell
Immediately call a POISON CENTER or doctor
IF ON SKIN: Wash with plenty of soap and water
Take off immediately all contaminated clothing
Take off contaminated clothing and wash before reuse
IF SWALLOWED: Immediately call a POISON CENTER or doctor
Rinse mouth
Store locked up
Store in a well-ventilated place. Keep container tightly closed
Dispose of contents/container to an approved waste disposal plant
Toxic to aquatic life with long lasting effects
WARNING. Reproductive Harm - https://www.p65warnings.ca.gov/.
Component CAS No Weight % Nicotine 54-11-5 >95
Show this safety data sheet to the doctor in attendance. Immediate medical attention is required.
Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Immediate medical attention is required.
Wash off immediately with plenty of water for at least 15 minutes. Immediate medical attention is required.
Remove to fresh air. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Immediate medical attention is required. If not breathing, give artificial respiration.
Do NOT induce vomiting. Call a physician or poison control center immediately.
No information available.
Treat symptomatically
Water spray, carbon dioxide (CO2), dry chemical, alcohol-resistant foam.
No information available
101 °C / 213.8 °F
No information available
240 °C / 464 °F
Upper 4.00 vol %
Lower 0.70 vol %
No information available
No information available
Vapors may form explosive mixture with air. Thermal decomposition can lead to release of irritating gases and vapors. Keep product and empty container away from heat and sources of ignition.
Nitrogen oxides (NOx). Carbon monoxide (CO). Carbon dioxide (CO 2).
As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear. Thermal decomposition can lead to release of irritating gases and vapors.
Use personal protective equipment as required. Ensure adequate ventilation. Keep people away from and upwind of spill/leak. Evacuate personnel to safe areas.
Do not flush into surface water or sanitary sewer system.
Soak up with inert absorbent material. Keep in suitable, closed containers for disposal.
Use only under a chemical fume hood. Wear personal protective equipment/face protection. Do not breathe mist/vapors/spray. Do not get in eyes, on skin, or on clothing. Do not ingest. If swallowed then seek immediate medical assistance.
Keep containers tightly closed in a dry, cool and well-ventilated place. Keep under nitrogen. Keep away from open flames, hot surfaces and sources of ignition. Incompatible Materials. Strong oxidizing agents. Strong acids. Strong bases.
Use only under a chemical fume hood. Ensure that eyewash stations and safety showers are close to the workstation location.
Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Wear appropriate protective gloves and clothing to prevent skin exposure.
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Organic gases and vapours filter. Type A. Brown. conforming to EN14387.
Handle in accordance with good industrial hygiene and safety practice.
Liquid
Colorless, Yellow, Brown
Fishy
No information available
-80 °C / -112 °F
No data available
247 °C / 476.6 °F @ 760 mmHg
101 °C / 213.8 °F
No information available
No data available
Not applicable
Liquid
Lower 0.7 Vol%
Upper 4 Vol%
240 - °C / 464 - °F
200°C
10.2 0.05M aq.sol
No data available
Miscible
No information available
0.53 mbar @ 25 °C
1.015
Not applicable
Liquid
5.61
1.17
Not applicable (liquid)
C10 H14 N2
162.23
None known, based on information available
Stable under normal conditions.
Incompatible products. Excess heat.
Strong oxidizing agents, Strong acids, Strong bases
Nitrogen oxides (NOx), Carbon monoxide (CO), Carbon dioxide (CO 2)
Hazardous polymerization does not occur.
None under normal processing.
Not an expected route of exposure.
May be harmful if swallowed.
Avoid contact with eyes.
Avoid contact with skin. Harmful in contact with skin.
No information available
No data available
No data available
No data available
No data available
No data available
No data available
No information available.
No data available
No information available.
This product does not contain any known or suspected endocrine disruptors.
Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. The product contains following substances which are hazardous for the environment.
Persistence is unlikely
No information available.
. Will likely be mobile in the environment due to its water solubility.
1.17
Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. Chemical waste generators must also consult local, regional, and national hazardous waste regulations to ensure complete and accurate classification.
UN1654
NICOTINE
6.1
II
UN1654
NICOTINE
6.1
II
UN1654
NICOTINE
6.1
II
UN1654
NICOTINE
6.1
II
Nicotine 54-11-5 X ACTIVE -
US EPA (TSCA) - Toxic Substances Control Act, (40 CFR Part 710)
X - Listed
'-' - Not Listed
Not applicable
Not applicable
Nicotine 54-11-5 X - 200-193-3 X X X X X KE-25325
KECL - NIER number or KE number (http://ncis.nier.go.kr/en/main.do)
This product contains a chemical or chemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372.
Nicotine 54-11-5 >95 1.0 % -
Should this product meet EPCRA 311/312 Tier reporting criteria at 40 CFR 370, refer to Section 2 of this SDS for appropriate classifications.
Not applicable
Not applicable
Not applicable
This material, as supplied, contains one or more substances regulated as a hazardous substance under the Comprehensive Environmental Response Compensation and Liability Act (CERCLA) (40 CFR 302) or the Superfund Amendments and Reauthorization Act (SARA) (40 CFR 355).
Nicotine 100 lb 100 lb 100 lb
45.4 kg
This product contains the following Proposition 65 chemicals.
Nicotine 54-11-5 Developmental - Developmental
Nicotine X X X X X
Y
N
N
This product does not contain any DHS chemicals.
Slight risk, Grade 1
Nicotine 54-11-5 -Use restricted. See entry 75. (see link for restriction details) -
https://echa.europa.eu/substances-restricted-under-reach
Nicotine 54-11-5 Not applicable Not applicable Not applicable Not applicable
Not applicable
Nicotine 54-11-5 Not applicable Not applicable Not applicable Not applicable
Product stewardship (Regulatory Affairs)
Thermo Fisher Scientific
email - begel.sdsdesk@thermofisher.com
03-Jun-2010
19-Dec-2025
19-Dec-2025
Updatedt ot heU .S.Departme ntofLabor’sOccupationalSafetyandH ealthA dmi nistration (OSHA) which published its Final Rule in the Federal Register revising the Hazard Communication Standard (HCS/HazCom), 29 CFR 1910.1200 (2024) (HCS §1910.1200, 2024), May 20, 2024, effective July 19, 2024.
The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text
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